Dr. Jianhua Ruan, Department of Computer Science, UTSA

Research Interests

Our research interests lie in the broad areas of bioinformatics and computational biology. We are interested in developing data-analytical methods and tools to make complex biological data more understandable and useful. We are also collaborating with biology labs in UTSA and UT Health Science Center - San Antonio to apply these methods to address theoretical and experimental questions in biology.

Specifically, we are currently developing algorithms in the following areas:

• Functional and structural properties of biological networks
  • Identifying topological properties to characterize biological networks
  • Data mining algorothms for biological networks
• Transcriptional and post-transcriptional regulatory networks
  • Identifying cis-regulatory elements and modules
• Microarray data analysis
  • Knowlege discovery from microarray data by statistical and graph-theoretical methods
• RNA secondary structure prediction

Research Support

Current

	National Institutes of Health National Institute of General Medical Sciences "Computational Discovery and Analysis of Community Structures in Biological Networks" $557,617, 1/01/09-12/31/12, PI
SALSI	San Antonio Life Sciences Institute "Molecular Changes in Aging Breast Stroma" $108,000, 2010/02/01-2011/08/31, PI
	National Science Foundation Division of Integrative Organismal Systems "A combined biochemical, molecular and computational approach to understanding the regulation of gibberellin biosynthesis in Arabidopsis" $150,000, 09/01/09-8/31/10 (with no-cost extension to 08/31/11), Co-PI PI: Valerie Sponsel
Completed
	University of Texas at San Antonio Faculty Research Award "Graph-theoretical Approaches to Knowledge Discovery from Gene Expression Microarray Data" $5,000, 2007-2008, PI

 

©2008 Jianhua Ruan